House MD is an American television medical drama that originally ran on the Fox network for eight seasons, The show's main character is Dr. Gregory House (Hugh Laurie), a pain medication-dependent, unconventional, misanthropic medical genius who leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey. The show's premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. Instead of criminals, the enemy is germs, diseases and other vulnerabilities of the human body, tracked down like criminals. But House isn't just derived from Holmes. The character may also have influences from other mythic characters.